Cytokine imbalance in pregnancies with fetal chromosomal abnormalities

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Cytokine imbalance in pregnancies with fetal chromosomal abnormalities.

BACKGROUND The aim of the present study is to investigate the levels of some of the cytokines which may be involved in the mechanisms leading to the impairment of placental perfusion and to the onset of uterine contractions in pregnancies with fetal genetic abnormalities compared with controls. METHODS The amniotic fluid and maternal plasma levels of interleukin-6, interleukin-8 and tumour ne...

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Background & Aims: Chromosome abnormalities are a major cause of miscarriage and neonatal mortality. The present study aimed to determine the association of fetal and parents chromosomal abnormalities with congenital anomalies. Methods: A cross-sectional study was performed in a tertiary referral center (Afzalipour Hospital) over 16 months period (2011-2012). The study groups consisted of 77 fe...

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Fetal Calcifications Are Associated with Chromosomal Abnormalities

OBJECTIVE The biological importance of calcifications occasionally noted in fetal tissues (mainly liver) at autopsy or ultrasound is largely unexplored. Previous reports hint at an association to infection, circulatory compromise, malformations or chromosomal abnormalities. To identify factors associated with calcifications, we have performed a case-control study on the largest cohort of fetuse...

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Screening for Fetal Chromosomal Abnormalities

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Screening for Fetal Chromosomal Abnormalities

This Practice Bulletin was developed by the ACOG Committee on Practice Bulletins—Obstetrics, the ACOG Com mittee on Genetics, and the Society for Maternal–Fetal Medicine Publications Com mit tee with the assistance of Ray Bahado-Singh, MD, and Deborah Driscoll, MD. The in for ma tion is de signed to aid practitioners in making decisions about appropriate obstetric and gyneco logic care. These g...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2002

ISSN: 0268-1161,1460-2350

DOI: 10.1093/humrep/17.3.803